Dupuytren’s contracture is a condition that develops over the course of many years and affects the hands and fingers. It begins with the thickening of the connective tissue within the palmar fascia, beneath the surface of palms. With time, lumps or knots develop beneath the palmar surface of the hand. Homeopathic medicines for Dupuytren’s Contracture can help arrest the progress of the disease in the early stages (before the permanent bending of the fingers). Silicea, Causticum, and Ruta are the top homeopathic medicines used to treat Dupuytren’s Contracture. The knots that develop as a result of the contracture mostly form at the base of the ring finger or the little finger. Eventually, hard cords develop from these knots that extend to the fingers. These cords contract with time, causing the bending or pulling of the affected fingers towards the palmar surface of the hand. With time, the fingers become deformed and the person is unable to extend the fingers in the long run. This leads to difficulty in performing everyday tasks like writing, holding objects, shaking hands, etc. The course of the condition varies from person to person. The disease may progress from initial stage to severe deformity in many cases while in others may not show progression up to the deformity stage. In many cases, Dupuytren’s contracture tends to self limit itself or even regresses in the initial stages itself.